Tupavirus global proteome - Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Synapt MS
ORGANISM(S): Tupavirus
SUBMITTER: 
DECLOQUEMENT Philippe
LAB HEAD: Eric CHABRIERE
PROVIDER: PXD007583 | Pride | 2018-10-24
REPOSITORIES: Pride
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Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere.
Abrahão Jônatas J Silva Lorena L Silva Ludmila Santos LS Khalil Jacques Yaacoub Bou JYB Rodrigues Rodrigo R Arantes Thalita T Assis Felipe F Boratto Paulo P Andrade Miguel M Kroon Erna Geessien EG Ribeiro Bergmann B Bergier Ivan I Seligmann Herve H Ghigo Eric E Colson Philippe P Levasseur Anthony A Kroemer Guido G Raoult Didier D La Scola Bernard B
Nature communications 20180227 1
Here we report the discovery of two Tupanvirus strains, the longest tailed Mimiviridae members isolated in amoebae. Their genomes are 1.44-1.51 Mb linear double-strand DNA coding for 1276-1425 predicted proteins. Tupanviruses share the same ancestors with mimivirus lineages and these giant viruses present the largest translational apparatus within the known virosphere, with up to 70 tRNA, 20 aaRS, 11 factors for all translation steps, and factors related to tRNA/mRNA maturation and ribosome prot ...[more]
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