Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Brain, Astrocyte
DISEASE(S): Glioblastoma
SUBMITTER: Enrique SantamarÃa
LAB HEAD: enrique santamaria
PROVIDER: PXD008022 | Pride | 2018-10-22
REPOSITORIES: Pride
Action | DRS | |||
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092todaslasfraccionesv2.group | Other | |||
092todaslasfraccionesv2__FDR.xlsx | Xlsx | |||
100mMB-092iTRAQ21092016-1.wiff | Wiff | |||
100mMB-092iTRAQ21092016-1.wiff.scan | Wiff | |||
125mMB-092iTRAQ21092016-2.wiff | Wiff |
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Oncotarget 20180724 57
Glioblastoma multiforme (GBM) is the most common and aggressive type of malignant glioma. Oncolytic adenoviruses are being modified to exploit the aberrant expression of proteins in tumor cells to increase the antiglioma efficacy. E1A mutant adenovirus Delta-24-RGD (DNX-2401) has shown a favorable toxicity profile and remarkable efficacy in a first-in-human phase I clinical trial. However, the comprehensive modulation of glioma metabolism in response to Delta-24-RGD infection is poorly understoo ...[more]