Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Embryonic Fibroblast, Cell Culture
SUBMITTER: Michael Hottiger
LAB HEAD: Michael O. Hottiger
PROVIDER: PXD008083 | Pride | 2017-12-14
REPOSITORIES: Pride
Items per page: 1 - 5 of 49 |
Nature communications 20171212 1
ADP-ribosylation is a posttranslational modification that exists in monomeric and polymeric forms. Whereas the writers (e.g. ARTD1/PARP1) and erasers (e.g. PARG, ARH3) of poly-ADP-ribosylation (PARylation) are relatively well described, the enzymes involved in mono-ADP-ribosylation (MARylation) have been less well investigated. While erasers for the MARylation of glutamate/aspartate and arginine have been identified, the respective enzymes with specificity for serine were missing. Here we report ...[more]