Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos, Q Exactive HF, Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cerebrospinal Fluid
DISEASE(S): Alzheimer's Disease
SUBMITTER: Akhilesh Pandey
LAB HEAD: Akhilesh Pandey
PROVIDER: PXD008098 | Pride | 2019-01-10
REPOSITORIES: Pride
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Sathe Gajanan G Na Chan Hyun CH Renuse Santosh S Madugundu Anil K AK Albert Marilyn M Moghekar Abhay A Pandey Akhilesh A Pandey Akhilesh A
Proteomics. Clinical applications 20190125 4
<h4>Purpose</h4>The aim of this study is to identify the potential cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease and to evaluate these markers on independent CSF samples using parallel reaction monitoring (PRM) assays.<h4>Experimental design</h4>High-Resolution mass spectrometry and tandem mass tag (TMT) multiplexing technology are employed to identify potential biomarkers for Alzheimer's disease. Some of the identified potential biomarkers are validated using PRM assays.<h4>Resul ...[more]