Proteomics

Dataset Information

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Evaluation of preservation quality and viability of FFPE ovarian cancer tissue samples


ABSTRACT: Analysis of 60 FFPE (formalin-fixed, paraffin-embedded) ovarian cancer tissue samples to evaluate preservation quality and viability of global and phosphoproteomic analysis

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Ovary

SUBMITTER: Matthew Monroe  

LAB HEAD: Karin Rodland

PROVIDER: PXD008832 | Pride | 2018-10-19

REPOSITORIES: Pride

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Publications


<h4>Background</h4>Mass spectrometry-based proteomics has become a powerful tool for the identification and quantification of proteins from a wide variety of biological specimens. To date, the majority of studies utilizing tissue samples have been carried out on prospectively collected fresh frozen or optimal cutting temperature (OCT) embedded specimens. However, such specimens are often difficult to obtain, in limited in supply, and clinical information and outcomes on patients are inherently d  ...[more]

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