Proteomics

Dataset Information

0

PROTEOMIC ANALYSIS OF EARLY DIABETIC RETINOPATHY REVEALS MEDIATORS OF NEURODEGENERATIVE BRAIN DISEASES


ABSTRACT: The aim of the present study was to identify early changes in diabetic retinas using an unbiased proteomics approach. Proteomic profiles of control retinas were compared to diabetic retinas obtained from patients known to have no classic vascular lesions that clinically define diabetic retinas. The diabetic retinas were further split into two groups according to the presence or absence of glial activation as marker of progressive changes that may be associated with the early neurodegenerative process. By examining differentially expressed proteins at this preclinical stage, our aim was to acquire a clearer understanding of the complex cellular processes that initiate diabetic retinas.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Retina

DISEASE(S): Diabetes Mellitus

SUBMITTER: Tatiana Laremore  

LAB HEAD: Jeffrey M. Sundstrom

PROVIDER: PXD008989 | Pride | 2022-03-02

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
14-08-18-YZC1-33.raw Raw
14-08-18-YZC10-15.raw Raw
14-08-18-YZC11-13.raw Raw
14-08-18-YZC12-11.raw Raw
14-08-18-YZC13-09.raw Raw
Items per page:
1 - 5 of 60

Similar Datasets

2023-05-10 | PXD037763 | Pride
2015-05-12 | E-GEOD-63737 | biostudies-arrayexpress
2017-04-03 | E-MTAB-4127 | biostudies-arrayexpress
2011-01-20 | E-MEXP-2555 | biostudies-arrayexpress
2014-02-27 | E-GEOD-55389 | biostudies-arrayexpress
2015-06-22 | E-GEOD-63993 | biostudies-arrayexpress
2014-08-11 | E-GEOD-31557 | biostudies-arrayexpress
2024-10-17 | PXD024300 | Pride
2010-08-15 | E-GEOD-21633 | biostudies-arrayexpress
2012-02-15 | E-GEOD-33014 | biostudies-arrayexpress