Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Liver, Cell Culture, Endothelial Cell
DISEASE(S): Liver Cirrhosis
SUBMITTER: Ana Maretti-Mira
LAB HEAD: Laurie D. DeLeve
PROVIDER: PXD009010 | Pride | 2018-11-06
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
Wang_TAA_1_1027.mgf | Mgf | |||
Wang_TAA_1_1027.mzid | Mzid | |||
Wang_TAA_1_1027.raw | Raw | |||
Wang_TAA_2_1027.mgf | Mgf | |||
Wang_TAA_2_1027.mzid | Mzid |
Items per page: 5 1 - 5 of 12 |
Maretti-Mira Ana C AC Wang Xiangdong X Wang Lei L DeLeve Laurie D LD
Hepatology (Baltimore, Md.) 20190207 3
Normal liver sinusoidal endothelial cells (LSECs) promote quiescence of hepatic stellate cells (HSCs). Prior to fibrosis, LSECs undergo capillarization, which is permissive for HSC activation, the proximate event in hepatic fibrosis. The aims of this study were to elucidate the nature of and mechanisms leading to capillarization and to determine how LSECs promote HSC quiescence and why "capillarized LSECs" lose control of HSC activation. The contribution of bone marrow (BM) endothelial progenito ...[more]