Proteomics

Dataset Information

0

Extracellular vesicles from Nippostrongylus brasiliensis


ABSTRACT: We identified the extracellular vesicles (EVs)secreted by the nematode Nippostrongylus brasiliensis. EV proteins were analysed using a 5600+ mass spectrometer (ABSCIEX).

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Nippostrongylus Brasiliensis

SUBMITTER: Ramon Eichenberger  

LAB HEAD: Alex Loukas

PROVIDER: PXD009165 | Pride | 2018-10-19

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20170602_Nb1.mgf Mgf
20170602_Nb1.pride.mgf.gz Mgf
20170602_Nb1.wiff Wiff
20170602_Nb1.wiff.scan Wiff
20170602_Nb10.mgf Mgf
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Publications


Gastrointestinal (GI) parasites, hookworms in particular, have evolved to cause minimal harm to their hosts, allowing them to establish chronic infections. This is mediated by creating an immunoregulatory environment. Indeed, hookworms are such potent suppressors of inflammation that they have been used in clinical trials to treat inflammatory bowel diseases (IBD) and celiac disease. Since the recent description of helminths (worms) secreting extracellular vesicles (EVs), exosome-like EVs from d  ...[more]

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