Dataset Information

Time-course phosphoproteome response during adenovirus type 2 infection

ABSTRACT: Time-course systematic and quantitative analysis combining TiO2 enrichment and SILAC to investigate changes in the phosphoproteome of Ad2 and IMR-90 cells after adenovirus infection

INSTRUMENT(S): Q Exactive

ORGANISM(S): Human Adenovirus C Serotype 2 (hadv-2) (human Adenovirus 2) Homo Sapiens (human)

TISSUE(S): Fibroblast Of Lung, Cell Culture

DISEASE(S): Viral Infectious Disease

SUBMITTER: Sara Lind

LAB HEAD: Sara Lind

PROVIDER: PXD009562 | Pride | 2020-07-03

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	MaxQuant1.5.7.4.zip	Other
	SILAC_Non_Phospho_Sample_A_1.raw	Raw
	SILAC_Non_Phospho_Sample_A_2.raw	Raw
	SILAC_Non_Phospho_Sample_B_1.raw	Raw
	SILAC_Non_Phospho_Sample_B_2.raw	Raw

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Publications

Phosphorylation Time-Course Study of the Response during Adenovirus Type 2 Infection.

Valdés Alberto A Zhao Hongxing H Pettersson Ulf U Lind Sara Bergström SB

Proteomics 20200225 7

PTMs such as phosphorylations are usually involved in signal transduction pathways. To investigate the temporal dynamics of phosphoproteome changes upon viral infection, a model system of IMR-90 cells infected with human adenovirus type 2 (Ad2) is used in a time-course quantitative analysis combining titanium dioxide (TiO<sub>2</sub> ) particle enrichment and SILAC-MS. Quantitative data from 1552 phosphorylated sites clustered the highly altered phosphorylated sites to the signaling by rho famil ...[more]

PMID: 32032466

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