Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Prostate Cancer Cell
DISEASE(S): Prostate Adenocarcinoma
SUBMITTER: Diego Iglesias-Gato
LAB HEAD: Diego Iglesias-Gato
PROVIDER: PXD009636 | Pride | 2019-09-11
REPOSITORIES: Pride
Items per page: 1 - 5 of 88 |
Clinical cancer research : an official journal of the American Association for Cancer Research 20181001 2
<h4>Purpose</h4>An increasing number of castration-resistant prostate cancer (CRPC) tumors exhibit neuroendocrine (NE) features. NE prostate cancer (NEPC) has poor prognosis, and its development is poorly understood.<b>Experimental Design:</b> We applied mass spectrometry-based proteomics to a unique set of 17 prostate cancer patient-derived xenografts (PDX) to characterize the effects of castration <i>in vivo</i>, and the proteome differences between NEPC and prostate adenocarcinomas. Genome-wi ...[more]