Dataset Information

Proteome analysis of B. bassiana

ABSTRACT: The enzymes involved (P450s) remain mostly hidden when using microbial cell factories. In this respect, we aimed to identify P450s, which are responsible for the oxyfunctionalization of DCF (1) and (R)-2-phenoxypropionic acid (POPS) in B. bassiana using omics studies.

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Beauveria Bassiana (strain Arsef 2860) (white Muscardine Disease Fungus) (tritirachium Shiotae)

SUBMITTER: Jan Klenk

LAB HEAD: Bernhard Hauer

PROVIDER: PXD009664 | Pride | 2019-06-12

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	BB_Dic (F018288).mzid_BB_Dic_(F018288).pride.mgf.gz	Mzid
	BB_Dic (F018288).pride.mztab.gz	Mztab
	BB_DicF018288.mzid.gz	Mzid
	BB_DicF018288.mzid_BB_Dic_F018288.MGF	Mzid
	BB_Dic_(F018288).pride.mgf.gz	Mgf

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Publications

Oxyfunctionalization of nonsteroidal anti-inflammatory drugs by filamentous-fungi.

Klenk J M JM Kontny L H LH Escobedo-Hinojosa W W Nebel B A BA Hauer B B

Journal of applied microbiology 20190703 3

<h4>Aims</h4>We aimed to expand the microbial biocatalyst platform to generate essential oxyfunctionalized standards for pharmaceutical, toxicological and environmental research. In particular, we examined the production of oxyfunctionalized nonsteroidal anti-inflammatory drugs (NSAIDs) by filamentous-fungi.<h4>Methods and results</h4>Four NSAIDs; diclofenac, ibuprofen, naproxen and mefenamic acid were used as substrates for oxyfunctionalization in a biocatalytic process involving three filament ...[more]

PMID: 31173436

Dataset Information

Proteome analysis of B. bassiana

Dataset's files

Publications

Oxyfunctionalization of nonsteroidal anti-inflammatory drugs by filamentous-fungi.

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