Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
DISEASE(S): Brain Glioblastoma Multiforme
SUBMITTER: Henriette Engen Berg
LAB HEAD: Henriette Engen Berg
PROVIDER: PXD010180 | Pride | 2019-04-10
REPOSITORIES: Pride
Action | DRS | |||
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IIY1_0-25kDa.msf | Msf | |||
IIY1_0-25kDa.raw | Raw | |||
IIY1_130-kDa.msf | Msf | |||
IIY1_130-kDa.raw | Raw | |||
IIY1_25-70k.raw | Raw |
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Journal of proteome research 20190418 5
Glioblastoma is the most common and malignant brain tumor, and current therapies confer only modest survival benefits. A major obstacle is our ability to monitor treatment effect on tumors. Current imaging modalities are ambiguous, and repeated biopsies are not encouraged. To scout for markers of treatment response, we used NMR spectroscopy to study the effects of a survivin inhibitor on the metabolome of primary glioblastoma cancer stem cells. Applying high resolution NMR spectroscopy (<sup>1</ ...[more]