Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human) Bos Taurus (bovine)
TISSUE(S): Blood Platelet
SUBMITTER: Christian Toonstra
LAB HEAD: Hui Zhang
PROVIDER: PXD010290 | Pride | 2019-06-14
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
Platelet_SetI_TMT.msf | Msf | |||
Platelet_TMT_SetII.msf | Msf | |||
Platelet_TMT_Set_II_Frac_1.mgf | Mgf | |||
Platelet_TMT_Set_II_Frac_1.raw | Raw | |||
Platelet_TMT_Set_II_Frac_10.mgf | Mgf |
Items per page: 5 1 - 5 of 104 |
Toonstra Christian C Hu Yingwei Y Zhang Hui H
Journal of proteome research 20190515 6
Collagen is a potent agonist for platelet activation, presenting itself as a key contributor to coagulation via interactions with platelet glycoproteins. The fine details dictating platelet-collagen interactions are poorly understood. In particular, glycosylation could be a key determinant in the platelet-collagen interaction. Here, we report an affinity purification coupled to a mass spectrometry-based approach to elucidate the function of N-glycans in dictating platelet-collagen interactions. ...[more]