Proteomics

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Multiomics resolution of molecular events during a day in the life of Chlamydomonas

ABSTRACT: Transcriptomic, proteomic, and metabolomic expression pattern analysis of Chlamydomonas reinhardtii's three genomes in cells grown under light-dark cycles

OTHER RELATED OMICS DATASETS IN: GSE112394

INSTRUMENT(S): Q Exactive

ORGANISM(S): Chlamydomonas Reinhardtii

TISSUE(S): Flagellate

SUBMITTER: Matthew Monroe  

LAB HEAD: Sabeeha Merchant

PROVIDER: PXD010794 | Pride | 2020-08-04

REPOSITORIES: Pride

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Chlam_cellcycle_01_Run1_23Nov16_Pippin_16-09-11.mgf Mgf
Chlam_cellcycle_01_Run1_23Nov16_Pippin_16-09-11.raw Raw
Chlam_cellcycle_01_Run1_23Nov16_Pippin_16-09-11_msgfplus.mzid.gz Mzid
Chlam_cellcycle_02_Run1_23Nov16_Pippin_16-09-11.mgf Mgf
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Multiomics resolution of molecular events during a day in the life of Chlamydomonas.

Strenkert Daniela D   Schmollinger Stefan S   Gallaher Sean D SD   Salomé Patrice A PA   Purvine Samuel O SO   Nicora Carrie D CD   Mettler-Altmann Tabea T   Soubeyrand Eric E   Weber Andreas P M APM   Lipton Mary S MS   Basset Gilles J GJ   Merchant Sabeeha S SS  

Proceedings of the National Academy of Sciences of the United States of America 20190118 6

The unicellular green alga <i>Chlamydomonas reinhardtii</i> displays metabolic flexibility in response to a changing environment. We analyzed expression patterns of its three genomes in cells grown under light-dark cycles. Nearly 85% of transcribed genes show differential expression, with different sets of transcripts being up-regulated over the course of the day to coordinate cellular growth before undergoing cell division. Parallel measurements of select metabolites and pigments, physiological  ...[more]

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