Dataset Information

S. cerevisiae natural isolate proteomics

ABSTRACT: Natural S. cerevisiae isolates were evaluated for tolerance to a complex mixture of lignocellulosic inhibitors. Two isolates, with intermediate and superior tolerance characteristics, were investigated to determine the proteomic changes required for tolerance to lignocellulosic inhibitors.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)

TISSUE(S): Cell Culture

SUBMITTER: Riaan Neethling de Witt

LAB HEAD: Heinrich Volschenk

PROVIDER: PXD010868 | Pride | 2018-11-02

REPOSITORIES: Pride

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Proteome response of two natural strains of Saccharomyces cerevisiae with divergent lignocellulosic inhibitor stress tolerance.

de Witt R N RN Kroukamp H H Volschenk H H

FEMS yeast research 20190101 1

Strains of Saccharomyces cerevisiae with improved tolerance to plant hydrolysates are of utmost importance for the cost-competitive production of value-added chemicals and fuels. However, engineering strategies are constrained by a lack of understanding of the yeast response to complex inhibitor mixtures. Natural S. cerevisiae isolates display niche-specific phenotypic and metabolic diversity, encoded in their DNA, which has evolved to overcome external stresses, utilise available resources and ...[more]

PMID: 30371771

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