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PAXX and its paralogues synergistically direct DNA polymerase I activity in DNA repair

ABSTRACT: In this study, we characterised the interactomes of PAXX and its paralogs, XLF and XRCC4, to show that these factors share the ability to interact with DNA polymerase lambda (Poll), stimulate its activityand are required for the recruitment of Poll to laser-induced DNA damage sites.

INSTRUMENT(S): Synapt MS

ORGANISM(S): Homo Sapiens (human)

DISEASE(S): Dna

SUBMITTER: Rebekah Jukes-Jones

LAB HEAD: Michal Malewicz

PROVIDER: PXD010891 | Pride | 2018-09-24

REPOSITORIES: Pride

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			Action	DRS
	AC_Pol_Bz_Con_A_30111701.raw.rar	Raw
	AC_Pol_Bz_Con_A_30111702.raw.rar	Raw
	AC_Pol_Bz_Con_A_30111703.raw.rar	Raw
	AC_Pol_Bz_Con_A_30111704.raw.rar	Raw
	AC_Pol_Bz_Con_A_30111705.raw.rar	Raw

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