Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Sanna Abbasi
LAB HEAD: Caroline Schild-Poulter
PROVIDER: PXD010931 | Pride | 2019-01-03
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
HEK293_Control.mzid.gz | Mzid | |||
HEK293_Control.pride.mztab.gz | Mztab | |||
HEK293_Control.raw | Raw | |||
Ku70_BioID_Rep_1.mzid.gz | Mzid | |||
Ku70_BioID_Rep_1.pride.mztab.gz | Mztab |
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Journal of proteome research 20190114 3
The Ku heterodimer, composed of Ku70 and Ku80, is best characterized for its role in repairing double-stranded DNA breaks but is also known to participate in other regulatory processes. Despite our understanding of Ku protein interplay during DNA repair, the extent of Ku's protein interactions in other processes has never been fully determined. Using proximity-dependent biotin identification (BioID) and affinity purification coupled to mass spectrometry (AP-MS) with wild-type Ku70, we identified ...[more]