Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600, LTQ
ORGANISM(S): Pseudomonas Aeruginosa Pao1
TISSUE(S): Whole Body
SUBMITTER: Wen-Ru Li
LAB HEAD: Wen-Ru Li
PROVIDER: PXD011144 | Pride | 2019-01-24
REPOSITORIES: Pride
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Frontiers in microbiology 20190107
Previously, we determined that diallyl disulfide (DADS) from garlic oil can inhibit <i>Pseudomonas aeruginosa</i> PAO1 pathogenic factors by inactivating the transcription of key genes from three quorum sensing (QS) systems (<i>las</i>, <i>rhl</i>, and <i>pqs</i>) based on the effects of DADS on growth, virulence factor production (elastase, pyocyanin, biofilm, and swarming motility), and RNA transcription (real-time q-PCR). To further investigate the mechanisms underlying the inhibition of the ...[more]