Proteomics

Dataset Information

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Native alpha synuclein crosslinking


ABSTRACT: Alpha synuclein in it's native state in solution was crosslinked using a variety of short-range crosslinking reagents. Crosslinks detected by mass spectrometry were then used as constraints in a discrete molecular dynamics simulation of the synuclein protein, and a structural ensemble of the protein was determined.

INSTRUMENT(S): LTQ Orbitrap Velos, Orbitrap Fusion

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Nicholas Brodie  

LAB HEAD: Christoph Borchers

PROVIDER: PXD011645 | Pride | 2019-02-28

REPOSITORIES: Pride

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