Native alpha synuclein crosslinking
Ontology highlight
ABSTRACT: Alpha synuclein in it's native state in solution was crosslinked using a variety of short-range crosslinking reagents. Crosslinks detected by mass spectrometry were then used as constraints in a discrete molecular dynamics simulation of the synuclein protein, and a structural ensemble of the protein was determined.
INSTRUMENT(S): LTQ Orbitrap Velos, Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Nicholas Brodie
LAB HEAD: Christoph Borchers
PROVIDER: PXD011645 | Pride | 2019-02-28
REPOSITORIES: Pride
ACCESS DATA