Dataset Information

Candida utilis as a protein source for Atlantic salmon

ABSTRACT: Single cell proteins, such as Candida utilis, are known to have immunomodulating effects in the distal intestine (DI) of Atlantic salmon, whereas soybean meal (SBM) can cause soybean meal induce enteritis (SBMIE). Inflammatory or immunomodulatory stimuli at the local level in the intestine may alter the plasma protein profile of Atlantic salmon. These changes can be helpful tools in diagnosis for fish diseases and indicators for fish health. The present work aimed to identify local intestinal tissue responses and changes in plasma protein profiles of Atlantic salmon fed C. utilis yeast, SBM, or combined diets. Fish meal (FM) based diet was used as a control diet and the six experimental diets were: FM diet with 200 g/kg C. utilis (FM200CU) and five diets containing 200 g/kg SBM together with 0 (SBM group), 25, 50, 100 or 200 g/kg C. utilis (SBM25CU, SBM50CU, SBM100CU and SBM200CU groups, respectively). Intestine morphology of fish fed FM200CU where not affected whereas SBM group presented changes characteristic of SBMIE. Low inclusion of C. utilis in SBM diet showed a modulation of immune cell populations, but did not alleviate inflammatory symptom.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Salmo Salar (atlantic Salmon)

TISSUE(S): Blood Cell, Blood Plasma

SUBMITTER: Leidy Lagos

LAB HEAD: Øverland, Margareth

PROVIDER: PXD012051 | Pride | 2020-05-18

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	171030_LagosLeidy.sf3	Other
	CJK_161122_Overland_Margarethe_01.mgf	Mgf
	CJK_161122_Overland_Margarethe_02.mgf	Mgf
	CJK_161122_Overland_Margarethe_03.mgf	Mgf
	CJK_161122_Overland_Margarethe_04.mgf	Mgf

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Publications

Candida utilis yeast as a functional protein source for Atlantic salmon (Salmo salar L.): Local intestinal tissue and plasma proteome responses.

Reveco-Urzua Felipe Eduardo FE Hofossæter Mette M Rao Kovi Mallikarjuna M Mydland Liv Torunn LT Ånestad Ragnhild R Sørby Randi R Press Charles McLean CM Lagos Leidy L Øverland Margareth M

PloS one 20191230 12

Microbial ingredients such as Candida utilis yeast are known to be functional protein sources with immunomodulating effects whereas soybean meal causes soybean meal-induced enteritis in the distal intestine of Atlantic salmon (Salmo salar L.). Inflammatory or immunomodulatory stimuli at the local level in the intestine may alter the plasma proteome profile of Atlantic salmon. These deviations can be helpful indicators for fish health and, therefore potential tools in the diagnosis of fish diseas ...[more]

PMID: 31887112

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