Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite, Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: Bernd Hessling
LAB HEAD: Felix T Wieland
PROVIDER: PXD012128 | Pride | 2019-01-07
REPOSITORIES: pride
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Adolf Frank F Rhiel Manuel M Hessling Bernd B Gao Qi Q Hellwig Andrea A Béthune Julien J Wieland Felix T FT
Cell reports 20190101 1
Intracellular transport and homeostasis of the endomembrane system in eukaryotic cells depend on the formation and fusion of vesicular carriers. Coat protein complex (COP) II vesicles export newly synthesized secretory proteins from the endoplasmic reticulum (ER), whereas COPI vesicles facilitate traffic from the Golgi to the ER and intra-Golgi transport. Mammalian cells express various isoforms of COPII and COPI coat proteins. To investigate the roles of coat protein paralogs, we have combined ...[more]