Dataset Information
Optimization of HUNTER N-termini profiling using rat brain proteome extracts
Ontology highlight
ABSTRACT:
INSTRUMENT(S): maXis
ORGANISM(S): Rattus Norvegicus (rat)
TISSUE(S): Brain
SUBMITTER: 
Fatih Demir
LAB HEAD: Pitter Florian Huesgen
PROVIDER: PXD012844 | Pride | 2019-09-03
REPOSITORIES: Pride
Dataset's files
Items per page: 1 - 5 of 9 |
Publications
Sensitive Determination of Proteolytic Proteoforms in Limited Microscale Proteome Samples.
Molecular & cellular proteomics : MCP 20190830 11
Protein N termini unambiguously identify truncated, alternatively translated or modified proteoforms with distinct functions and reveal perturbations in disease. Selective enrichment of N-terminal peptides is necessary to achieve proteome-wide coverage for unbiased identification of site-specific regulatory proteolytic processing and protease substrates. However, many proteolytic processes are strictly confined in time and space and therefore can only be analyzed in minute samples that provide i ...[more]
