Proteomics

Dataset Information

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Quantitative Proteomics to Study Aging in Rabbit Liver


ABSTRACT: This project describes the quatitative changes in the rabbit liver in response of increasing age. Quantitative proteomics workflow was used to track metabolic changes that occur in the rabbit liver with elderly. Three age groups (young, middle, and old age rabbits were quantitatively compared and enrich classes of proteins involved in mitochondrial dysfunction, protein, carbohydrate, and fat metabolism were detected.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Oryctolagus Cuniculus (rabbit)

TISSUE(S): Liver

SUBMITTER: Bushra Amin  

LAB HEAD: Renã AS Robinson

PROVIDER: PXD013220 | Pride | 2020-03-19

REPOSITORIES: pride

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Publications

Dataset of quantitative proteomic analysis to understand aging processes in rabbit liver.

Amin Bushra B   Robinson Renã A S RAS  

Data in brief 20200515


Here, we present a proteomics dataset of liver proteins to understand aging in rabbits, which complements the publication "Quantitative proteomics to study aging in rabbit liver" [1]. This dataset was generated to understand the molecular basis and metabolic changes of aging processes in liver, which is the main organ involved in metabolism, detoxification, transport, and signaling. Proteins from young, middle, and old age rabbits were extracted and digested. Generated peptides were labeled with  ...[more]

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