Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Ovary, Breast
DISEASE(S): Head And Neck Cancer,Malignant Neoplasm Of Ovary,Breast Cancer
SUBMITTER: Roberta Noberini
LAB HEAD: Tiziana Bonaldi
PROVIDER: PXD013311 | Pride | 2019-09-09
REPOSITORIES: Pride
Cancers 20190524 5
Aberrations in histone post-translational modifications (PTMs), as well as in the histone modifying enzymes (HMEs) that catalyze their deposition and removal, have been reported in many tumors and many epigenetic inhibitors are currently under investigation for cancer treatment. Therefore, profiling epigenetic features in cancer could have important implications for the discovery of both biomarkers for patient stratification and novel epigenetic targets. In this study, we employed mass spectrome ...[more]