Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Plasma Cell
DISEASE(S): Multiple Myeloma
SUBMITTER: Srikanth Rapole
LAB HEAD: Srikanth Rapole
PROVIDER: PXD013859 | Pride | 2019-09-09
REPOSITORIES: Pride
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Chanukuppa Venkatesh V Paul Debasish D Taunk Khushman K Chatterjee Tathagata T Sharma Sanjeevan S Kumar Saravanan S Santra Manas K MK Rapole Srikanth S
Journal of proteomics 20190826
Among the blood cancers, 13% mortality is caused by Multiple myeloma (MM) type of hematological malignancy. In spite of therapeutic advances in chemotherapy treatment, still MM remains an incurable disease is mainly due to emergence of chemoresistance. At present time, FDA approved bortezomib is the first line drug for MM treatment. However, like other chemotherapy, MM patients are acquiring resistance against bortezomib. The present study aims to identify and validate bortezomib resistant prote ...[more]