Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive Plus
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Skeletal Muscle, Myotube
SUBMITTER: Fabrice BERTILE
LAB HEAD: Sarah Cianférani
PROVIDER: PXD014126 | Pride | 2020-05-26
REPOSITORIES: Pride
Action | DRS | |||
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MQresults_Myotubes_EPS_secretome.zip | Other | |||
QE17863PAM.raw | Raw | |||
QE17864PAM.raw | Raw | |||
QE17865PAM.raw | Raw | |||
QE17866PAM.raw | Raw |
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Laurens Claire C Parmar Anisha A Murphy Enda E Carper Deborah D Lair Benjamin B Maes Pauline P Vion Julie J Boulet Nathalie N Fontaine Coralie C Marquès Marie M Larrouy Dominique D Harant Isabelle I Thalamas Claire C Montastier Emilie E Caspar-Bauguil Sylvie S Bourlier Virginie V Tavernier Geneviève G Grolleau Jean-Louis JL Bouloumié Anne A Langin Dominique D Viguerie Nathalie N Bertile Fabrice F Blanc Stéphane S de Glisezinski Isabelle I O'Gorman Donal D Moro Cedric C
JCI insight 20200326 6
We hypothesized that skeletal muscle contraction produces a cellular stress signal, triggering adipose tissue lipolysis to sustain fuel availability during exercise. The present study aimed at identifying exercise-regulated myokines, also known as exerkines, able to promote lipolysis. Human primary myotubes from lean healthy volunteers were submitted to electrical pulse stimulation (EPS) to mimic either acute intense or chronic moderate exercise. Conditioned media (CM) experiments with human adi ...[more]