Proteomics

Dataset Information

0

GRASP Proximity Labeling


ABSTRACT: The goal of the project is to identify interactors of GRASP, a golgi-associated protein, to elucidate the mechanism of unconventional secretion.

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Yu-Hsiu Lin  

LAB HEAD: Jayanta Debnath

PROVIDER: PXD014247 | Pride | 2021-10-02

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
HUMAN.fasta Fasta
OxidationMSites.txt Txt
PhosphoSTYSites.txt Txt
Q20161021-08G2A_bR1.raw Raw
Q20161021-10WT_bR1.raw Raw
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Publications

GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network.

Liu Jennifer Y JY   Lin Yu-Hsiu Tony YT   Leidal Andrew M AM   Huang Hector H HH   Ye Jordan J   Wiita Arun P AP   Debnath Jayanta J  

Biology open 20211012 10


There is great interest in understanding the cellular mechanisms controlling autophagy, a tightly regulated catabolic and stress-response pathway. Prior work has uncovered links between autophagy and the Golgi reassembly stacking protein of 55 kDa (GRASP55), but their precise interrelationship remains unclear. Intriguingly, both autophagy and GRASP55 have been functionally and spatially linked to the endoplasmic reticulum (ER)---Golgi interface, broaching this compartment as a site where GRASP55  ...[more]

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