Proteomics

Dataset Information

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Global proteomics profile of Yeast during cysteine treatment


ABSTRACT: Cell requires optimal amount of nutrients for the synthesis of macromolecules like lipid, protein and nucleotides. There is a very limited knowledge about how cells maintain homeostasis in excess nutrients. By using Yeast as a model system we have shown that some aminoacids are toxic at higher concentration. We have chosen cysteine as a physiologically relevant example and using proteomics approach we delineated the altered pathways/ metabolic processes .We found that cysteine alters proteins mainly involved in amino acid metabolism, energy metabolism and proteins involved in translation.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)

DISEASE(S): Cardiovascular System Disease

SUBMITTER: Rahul Chakraborty  

LAB HEAD: shantanu sengupta

PROVIDER: PXD014859 | Pride | 2019-08-13

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
Bio1_4plex.mgf Mgf
Bio1_4plex.mzXML Mzxml
Bio2_4plex.mgf Mgf
Bio2_4plex.mzXML Mzxml
Bio3_4plex.mgf Mgf
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