Proteomics

Dataset Information

0

Chinese giant salamander liver LC-MS/MS


ABSTRACT: Chinese giant salamander Andrias davidianus has strong tolerance to starvation. Here, a high-throughput proteomic analysis was carried out on liver samples obtained from the A. davidianus after 3, 7 and 11 months of fasting.s a result, the expression levels of 364 proteins were significantly changed in the fasted liver. This study provides insights into the molecular mechanisms underlying the metabolic response of A. davidianus liver to fasting.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Andrias Davidianus

TISSUE(S): Liver

SUBMITTER: Xiaofang Geng  

LAB HEAD: Xiaofang Geng

PROVIDER: PXD014924 | Pride | 2020-01-17

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
Proteinquantitation.xlsx Xlsx
ZB07161313gan201610141.group Other
ZB07161313i102016101410.wiff Wiff
ZB07161313i1201610141.wiff Wiff
ZB07161313i2201610142.wiff Wiff
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Publications

Differential Proteomic Analysis of Chinese Giant Salamander Liver in Response to Fasting.

Geng Xiaofang X   Guo Jianlin J   Zhang Lu L   Sun Jiyao J   Zang Xiayan X   Qiao Zhigang Z   Xu Cunshuan C  

Frontiers in physiology 20200318


Chinese giant salamander <i>Andrias davidianus</i> has strong tolerance to starvation. Fasting triggers a complex array of adaptive metabolic responses, a process in which the liver plays a central role. Here, a high-throughput proteomic analysis was carried out on liver samples obtained from adult <i>A. davidianus</i> after 3, 7, and 11 months of fasting. As a result, the expression levels of 364 proteins were significantly changed in the fasted liver. Functional analysis demonstrated that the  ...[more]

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