Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Bordetella Pertussis (strain Tohama I / Atcc Baa-589 / Nctc 13251) Bordetella Pertussis
SUBMITTER: Denisa Petrackova
LAB HEAD: Branislav Večerek
PROVIDER: PXD015184 | Pride | 2021-09-08
REPOSITORIES: pride
Dienstbier Ana A Amman Fabian F Petráčková Denisa D Štipl Daniel D Čapek Jan J Zavadilová Jana J Fabiánová Kateřina K Držmíšek Jakub J Kumar Dilip D Wildung Mark M Pouchnik Derek D Večerek Branislav B
Emerging infectious diseases 20210101 1
Despite high vaccination coverage, pertussis is increasing in many industrialized countries, including the Czech Republic. To better understand Bordetella pertussis resurgence, we analyzed historic strains and recent clinical isolates by using a comparative omics approach. Whole-genome sequencing showed that historic and recent isolates of B. pertussis have substantial variation in genome organization and form separate phylogenetic clusters. Subsequent RNA sequence analysis and liquid chromatogr ...[more]