Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Román González-Prieto
LAB HEAD: Román González-Prieto
PROVIDER: PXD015437 | Pride | 2019-11-15
REPOSITORIES: Pride
Action | DRS | |||
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RNF4-TULIP2conjugatestxtfolder.zip | Other | |||
TULIPvsTULIP2txtfolder.zip | Other | |||
q103328a.raw | Raw | |||
q103337a.raw | Raw | |||
q103346a.raw | Raw |
Items per page: 5 1 - 5 of 11 |
Salas-Lloret Daniel D Agabitini Giulia G González-Prieto Román R
Frontiers in chemistry 20191126
Protein modification by Ubiquitin or Ubiquitin-like modifiers is mediated by an enzyme cascade composed of E1, E2, and E3 enzymes. E1s, or ubiquitin-activating enzymes, perform ubiquitin activation. Next, ubiquitin is transferred to ubiquitin-conjugating enzymes or E2s. Finally, ubiquitin ligases or E3s catalyze the transfer of ubiquitin to the acceptor proteins. E3 enzymes are responsible for determining the substrate specificity. Determining which E3 enzyme maps to which substrate is a major c ...[more]