Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Peripheral Blood Mononuclear Cell
DISEASE(S): Acute Myeloid Leukemia
SUBMITTER: Annika Nelde
LAB HEAD: Juliane S. Walz (neé Stickel)
PROVIDER: PXD015748 | Pride | 2019-10-14
REPOSITORIES: pride
Action | DRS | |||
---|---|---|---|---|
UPN11_class_I_Rep1.msf | Msf | |||
UPN11_class_I_Rep1.raw | Raw | |||
UPN11_class_I_Rep2.RAW | Raw | |||
UPN11_class_I_Rep2.msf | Msf | |||
UPN11_class_I_Rep3.RAW | Raw |
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Leukemia 20140805 3
Identification of physiologically relevant peptide vaccine targets calls for the direct analysis of the entirety of naturally presented human leukocyte antigen (HLA) ligands, termed the HLA ligandome. In this study, we implemented this direct approach using immunoprecipitation and mass spectrometry to define acute myeloid leukemia (AML)-associated peptide vaccine targets. Mapping the HLA class I ligandomes of 15 AML patients and 35 healthy controls, more than 25 000 different naturally presented ...[more]