Proteomics

Dataset Information

0

The GTPase Rab39a matures phagosomes into MHC-I antigen-presenting compartments.


ABSTRACT: We have found Rab39a to be important in dendritic cells to promote antigen crosspresentation. As Rab39a is a Rab GTPase, we sought to determine how it influenced the contents of phagosomes. Thus we used SILAC using Rab39a CRISPR KO or reconstituted cells to determine phagosomal protein differences using a proteomics based approach.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Dendritic Cell

SUBMITTER: Freidrich Cruz  

LAB HEAD: Kenneth Rock

PROVIDER: PXD016394 | Pride | 2019-12-11

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
102617Cruz_SILAC_1.raw Raw
102617Cruz_SILAC_2.raw Raw
102617Cruz_SILAC_3.raw Raw
110917Cruz_SILAC_1.raw Raw
110917Cruz_SILAC_2.raw Raw
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