Proteomics

Dataset Information

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Sus scrofa, skeletal muscle, LC-MSMS

ABSTRACT: Skeletal muscle were collected from pigs treated in the control group, the Lys deficiency group and the Lys rescue group. Then, the samples were analyzed by LC-MSMS.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Sus Scrofa Domesticus (domestic Pig)

TISSUE(S): Skeletal Muscle

SUBMITTER: Cheng-long Jin  

LAB HEAD: Xiu-qi Wang

PROVIDER: PXD016396 | Pride | 2020-05-27

REPOSITORIES: Pride

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Publications

mTORC1 Mediates Lysine-Induced Satellite Cell Activation to Promote Skeletal Muscle Growth.

Jin Cheng-Long CL   Ye Jin-Ling JL   Yang Jinzeng J   Gao Chun-Qi CQ   Yan Hui-Chao HC   Li Hai-Chang HC   Wang Xiu-Qi XQ  

Cells 20191130 12

As the first limiting amino acid, lysine (Lys) has been thought to promote muscle fiber hypertrophy by increasing protein synthesis. However, the functions of Lys seem far more complex than that. Despite the fact that satellite cells (SCs) play an important role in skeletal muscle growth, the communication between Lys and SCs remains unclear. In this study, we investigated whether SCs participate directly in Lys-induced skeletal muscle growth and whether the mammalian target of rapamycin complex  ...[more]