Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion ETD
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Hippocampus
SUBMITTER: Alfonsina D'Amato
LAB HEAD: Alfonsina D'Amato
PROVIDER: PXD016432 | Pride | 2021-09-09
REPOSITORIES: Pride
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D'Amato Alfonsina A Di Cesare Mannelli Lorenzo L Lucarini Elena E Man Angela L AL Le Gall Gwenaelle G Branca Jacopo J V JJV Ghelardini Carla C Amedei Amedeo A Bertelli Eugenio E Regoli Mari M Pacini Alessandra A Luciani Giulia G Gallina Pasquale P Altera Annalisa A Narbad Arjan A Gulisano Massimo M Hoyles Lesley L Vauzour David D Nicoletti Claudio C
Microbiome 20201001 1
<h4>Background</h4>The gut-brain axis and the intestinal microbiota are emerging as key players in health and disease. Shifts in intestinal microbiota composition affect a variety of systems; however, evidence of their direct impact on cognitive functions is still lacking. We tested whether faecal microbiota transplant (FMT) from aged donor mice into young adult recipients altered the hippocampus, an area of the central nervous system (CNS) known to be affected by the ageing process and related ...[more]