Proteomics

Dataset Information

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Quantitative proteomic analysis of CKD urine samples


ABSTRACT: Urinary proteomics studies have primarily focused on identifying markers of chronic kidney disease (CKD) progression. Here, we aimed to specify CKD-related injury markers through proteomics analysis in urine of patients with CKD. Label-free quantitative proteomics analysis based on liquid chromatography-tandem mass spectrometry was performed on urine samples obtained from 6, 9, 11, and 10 patients in health control, CKD stage 1, 3 and 5, respectively.

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Urine

DISEASE(S): Chronic Kidney Disease

SUBMITTER: Dohyun Han  

LAB HEAD: Dohyun Han

PROVIDER: PXD016433 | Pride | 2021-01-19

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20190408_CKD_1_1_F1.raw Raw
20190408_CKD_1_1_F2.raw Raw
20190408_CKD_1_1_F3.raw Raw
20190408_CKD_1_2_F1.raw Raw
20190408_CKD_1_2_F2.raw Raw
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Publications

Multisample Mass Spectrometry-Based Approach for Discovering Injury Markers in Chronic Kidney Disease.

Kim Ji Eun JE   Han Dohyun D   Jeong Jin Seon JS   Moon Jong Joo JJ   Moon Hyun Kyung HK   Lee Sunhwa S   Kim Yong Chul YC   Yoo Kyung Don KD   Lee Jae Wook JW   Kim Dong Ki DK   Kwon Young Joo YJ   Kim Yon Su YS   Yang Seung Hee SH  

Molecular & cellular proteomics : MCP 20210113


Urinary proteomics studies have primarily focused on identifying markers of chronic kidney disease (CKD) progression. Here, we aimed to determine urinary markers of CKD renal parenchymal injury through proteomics analysis in animal kidney tissues and cells and in the urine of patients with CKD. Label-free quantitative proteomics analysis based on liquid chromatography-tandem mass spectrometry was performed on urine samples obtained from 6 normal controls and 9, 11, and 10 patients with CKD stage  ...[more]

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