Protein identification in mouse liver by LC-MSMS
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF-X
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Hepatocyte, Liver
SUBMITTER: 
Yiguo Wang
LAB HEAD: Yiguo Wang
PROVIDER: PXD016917 | Pride | 2020-02-17
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| TJP1-interactingproteins.mgf | Mgf | |||
| TJP1-interactingproteins.pep.xml | Pepxml | |||
| TJP1-interactingproteins.raw | Raw |
Items per page: 5 1 - 3 of 3 |
Publications
The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock.
Liu Yi Y Zhang Yuanyuan Y Li Tong T Han Jinbo J Wang Yiguo Y
Nature communications 20200130 1
Circadian clocks in the suprachiasmatic nucleus and peripheral tissues orchestrate behavioral and physiological activities of mammals in response to environmental cues. In the liver, the circadian clock is also modulated by feeding. However, the molecular mechanisms involved are unclear. Here, we show that TJP1 (tight junction protein 1) functions as a mediator of mTOR (mechanistic target of rapamycin) to modulate the hepatic circadian clock. TJP1 interacts with PER1 (period circadian regulator ...[more]
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