Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion, Q Exactive HF
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Brain
DISEASE(S): Parkinson's Disease
SUBMITTER: Renze Ma
LAB HEAD: Michael Fitzgerald
PROVIDER: PXD016985 | Pride | 2021-09-19
REPOSITORIES: Pride
Items per page: 1 - 5 of 192 |
Journal of proteome research 20211004 11
Here, we utilize the stability of proteins from rates of oxidation (SPROX) technique, to profile the thermodynamic stabilities of proteins in brain tissue cell lysates from Huα-Syn(A53T) transgenic mice at three time points including at 1 month (<i>n</i> = 9), at 6 months (<i>n</i> = 7), and at the time (between 9 and 16 months) a mouse became symptomatic (<i>n</i> = 8). The thermodynamic stability profiles generated here on 332 proteins were compared to thermodynamic stability profiles generate ...[more]