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Serum and urinary proteomes between healthy dogs and dogs with renal dysfunction in babesiosis using label-based high-resolution quantitative proteomics

ABSTRACT: The aim of the study was to analyse differences in serum and urinary proteomes between healthy dogs and dogs with renal dysfunction in babesiosis using label-based high-resolution quantitative proteomic approach. In the study 8 healthy control dogs (group H) and 22 dogs with naturally occurring babesiosis were enrolled. Dogs with babesiosis were divided into 3 groups: group A consisted of 6 non-azotaemic dogs (serum creatinine <140 μmol/L) with normal UPC (UPC < 0.5), group B of 10 non-azotaemic dogs with proteinuria (UPC > 0.5) and group C of 6 azotaemic dogs (serum creatinine > 140 μmol/L) and significant proteinuria (UPC > 2).

INSTRUMENT(S): Q Exactive

ORGANISM(S): Canis Familiaris (dog) (canis Lupus Familiaris)

TISSUE(S): Urine, Blood Serum

DISEASE(S): Babesiosis

SUBMITTER: Anita Horvatic

LAB HEAD: Peter David Eckersall

PROVIDER: PXD017263 | Pride | 2022-10-18

REPOSITORIES: Pride

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			Action	DRS
	20170418_petra_serumi_sixplex1.mgf	Mgf
	20170418_petra_serumi_sixplex1.raw	Raw
	20170419_petra_serumi_sixplex2.mgf	Mgf
	20170419_petra_serumi_sixplex2.raw	Raw
	20170419_petra_serumi_sixplex4.mgf	Mgf

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