Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Velos
ORGANISM(S): Neurospora Crassa
SUBMITTER: Phillip Wilmarth
LAB HEAD: Eric U. Selker
PROVIDER: PXD017300 | Pride | 2021-07-21
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
HON1294_6_20121219_VE.raw | Raw | |||
HON1294_6_20121219_VE_filtered.ms2 | Other | |||
HON1294_6_20121219_VE_filtered.sqt | Other | |||
HON1294_6_20121219_VE_filtered.txt | Txt | |||
HON1294_peptide_summary_6.txt | Txt |
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Nucleic acids research 20201001 18
Heterochromatin is a specialized form of chromatin that restricts access to DNA and inhibits genetic processes, including transcription and recombination. In Neurospora crassa, constitutive heterochromatin is characterized by trimethylation of lysine 9 on histone H3, hypoacetylation of histones, and DNA methylation. We explored whether the conserved histone demethylase, lysine-specific demethylase 1 (LSD1), regulates heterochromatin in Neurospora, and if so, how. Though LSD1 is implicated in het ...[more]