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Cajanin Stilbene Acid Inhibited Vancomycin-Resistant Enterococci By Inhibiting Phosphotransferase System

ABSTRACT: In order to determine the mechanism of Cajanin Stilbene Acid inhibiting vancomycin-resistant enterococci, we compared the changes in protein expression of enterococci V583 strain before and after treated by Cajanin Stilbene Acid.

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Enterococcus Faecium

SUBMITTER: Xin Hua

LAB HEAD: Xin Hua

PROVIDER: PXD017522 | Pride | 2020-05-27

REPOSITORIES: Pride

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Publications

Cajanin Stilbene Acid Inhibited Vancomycin-Resistant Enterococcus by Inhibiting Phosphotransferase System.

Tan Shengnan S Hua Xin X Xue Zheyong Z Ma Jianzhang J

Frontiers in pharmacology 20200415

Antimicrobial resistance has become a serious threat to human and animal health, and vancomycin-resistant Enterococcus has become an important nosocomial infection pathogen, causing thousands of deaths each year. In this study, after screening a variety of natural products, we found that cajanin stilbene acid (CSA) had significant inhibitory effect on sensitive and vancomycin-resistant Enterococcus (VRE) in vitro. And we also confirmed that CSA had significant anti-VRE infec ...[more]

PMID: 32372958

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