Proteomics

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Pilot evaluation of two Fasciola hepatica biomarkers for supporting TCBZ efficacy diagnostics


ABSTRACT: Two Fasciola hepatica biomarkers, calreticulin and triose phosphate isomerase, of prospective diagnostic potential were recombinantly expressed and analysed through gel-based proteomics and liquid chromatography and tandem mass spectrometry (LC-MS/MS). Formal identifications through tandem mass spectrometry were ascertained as a prerequisite to immunologic evaluations.

INSTRUMENT(S): 6550 iFunnel Q-TOF LC/MS

ORGANISM(S): Fasciola Hepatica (liver Fluke)

SUBMITTER: Clare Collett  

LAB HEAD: Professor Peter Brophy

PROVIDER: PXD017848 | Pride | 2020-07-31

REPOSITORIES: Pride

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