The lncRNA Growth Arrest Specific 5 regulates cell survival via distinct structural modules with independent functions
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: 
Duc Duong
LAB HEAD: Eric Ortlund
PROVIDER: PXD018584 | Pride | 2021-04-07
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| OxidationMSites.txt | Txt | |||
| Uniprot_HUMAN_042015plusApoEisoformsABETA.fasta | Fasta | |||
| allPeptides.txt | Txt | |||
| eort_rna_a01.raw | Raw | |||
| eort_rna_a02.raw | Raw |
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Publications
The lncRNA Growth Arrest Specific 5 Regulates Cell Survival via Distinct Structural Modules with Independent Functions.
Frank Filipp F Kavousi Nadieh N Bountali Aikaterini A Dammer Eric B EB Mourtada-Maarabouni Mirna M Ortlund Eric A EA
Cell reports 20200701 3
There is increasing evidence that the architecture of long non-coding RNAs (lncRNAs)-just like that of proteins-is hierarchically organized into independently folding sub-modules with distinct functions. Studies characterizing the cellular activities of such modules, however, are rare. The lncRNA growth arrest specific 5 (GAS5) is a key regulator of cell survival in response to stress and nutrient availability. We use SHAPE-MaP to probe the structure of GAS5 and identify three separate structura ...[more]
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