Dataset Information

Salivary proteome in canine pyometra

ABSTRACT: The aims were to explore whether saliva composition could reflect the physiopathological changes occurring in canine pyometra and to identify potential biomarkers of the disease using a high-throughput quantitative proteomic analysis. Saliva samples from six healthy (H) and six bitches with pyometra (P) were analysed using Tandem Mass Tags (TMT) - based approach.

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Canis Familiaris (dog) (canis Lupus Familiaris)

TISSUE(S): Saliva

DISEASE(S): Uterine Inflammatory Disease

SUBMITTER: Anita Horvatic

LAB HEAD: Peter David Eckersall

PROVIDER: PXD018692 | Pride | 2020-04-27

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	20190403_Lorena_canine_pyo_saliva_TMT_all_PSMs.txt	Txt
	20190403_Lorena_canine_pyo_saliva_TMT_all_PeptideGroups.txt	Txt
	20190403_Lorena_canine_pyo_saliva_TMT_all_ProteinGroups.txt	Txt
	20190403_Lorena_canine_pyo_saliva_TMT_all_Proteins.txt	Txt
	20190404_Lorena_caninePyo_saliva_TMTsix1.mgf	Mgf

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Publications

Changes in the Salivary Proteome Associated With Canine Pyometra.

Franco-Martínez Lorena L Horvatić Anita A Gelemanović Andrea A Samardžija Marko M Mrljak Vladimir V Contreras-Aguilar María Dolores MD Martínez-Subiela Silvia S Dąbrowski Roman R Tvarijonaviciute Asta A

Frontiers in veterinary science 20200611

The present study evaluated for the first time changes in the saliva proteome in bitches with pyometra through a high-throughput quantitative proteomic analysis. The aims were to explore whether saliva composition could reflect the physiopathological changes occurring in canine pyometra and to identify potential biomarkers of the disease. Saliva samples from six healthy (H) and six bitches with pyometra (P) were analyzed using tandem mass tags-based approach. Additionally, 15 samples were used f ...[more]

PMID: 32596263

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