Dataset Information
Scorpion (Centruroides vittatus) venom gland
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Centruroides Vittatus
TISSUE(S): Diploid Cell, Telson
DISEASE(S): Disease Free
SUBMITTER: 
tsunemi yamashita
LAB HEAD: Tsunemi Yamashita
PROVIDER: PXD019850 | Pride | 2022-02-15
REPOSITORIES: Pride
Dataset's files
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Publications
Reduced Toxicity of <i>Centruroides vittatus</i> (Say, 1821) May Result from Lowered Sodium β Toxin Gene Expression and Toxin Protein Production.
Toxins 20211122 11
Body tissue and venom glands from an eastern population of the scorpion <i>Centruroides vittatus</i> (Say, 1821) were homogenized and molecular constituents removed to characterize putative sodium β toxin gene diversity, RT-qPCR, transcriptomic, and proteomic variation. We cloned sodium β toxins from genomic DNA, conducted RT-qPCR experiments with seven sodium β toxin variants, performed venom gland tissue RNA-seq, and isolated venom proteins for mass spectrophotometry. We identified >70 putativ ...[more]
