Ontology highlight
ABSTRACT:
INSTRUMENT(S): micrOTOF II
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Urine
DISEASE(S): Iga Glomerulonephritis
SUBMITTER: Martin Pejchinovski
LAB HEAD: Martin Pejchinovski
PROVIDER: PXD020288 | Pride | 2022-02-15
REPOSITORIES: Pride
Rudnicki Michael M Siwy Justyna J Wendt Ralph R Lipphardt Mark M Koziolek Michael J MJ Maixnerova Dita D Peters Björn B Kerschbaum Julia J Leierer Johannes J Neprasova Michaela M Banasik Miroslaw M Sanz Ana Belen AB Perez-Gomez Maria Vanessa MV Ortiz Alberto A Stegmayr Bernd B Tesar Vladimir V Mischak Harald H Beige Joachim J Reich Heather N HN
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20211201 1
<h4>Background</h4>Risk of kidney function decline in immunoglobulin A (IgA) nephropathy (IgAN) is significant and may not be predicted by available clinical and histological tools. To serve this unmet need, we aimed at developing a urinary biomarker-based algorithm that predicts rapid disease progression in IgAN, thus enabling a personalized risk stratification.<h4>Methods</h4>In this multicentre study, urine samples were collected in 209 patients with biopsy-proven IgAN. Progression was define ...[more]