Proteomics

Dataset Information

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Urine proteomics in IgA nephropathy


ABSTRACT: we aimed at developing a urinary biomarker-based algorithm that predicts rapid disease progression in IgAN, thus enabling a personalized risk stratification.

INSTRUMENT(S): micrOTOF II

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Urine

DISEASE(S): Iga Glomerulonephritis

SUBMITTER: Martin Pejchinovski  

LAB HEAD: Martin Pejchinovski

PROVIDER: PXD020288 | Pride | 2022-02-15

REPOSITORIES: Pride

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Publications

Urine proteomics for prediction of disease progression in patients with IgA nephropathy.

Rudnicki Michael M   Siwy Justyna J   Wendt Ralph R   Lipphardt Mark M   Koziolek Michael J MJ   Maixnerova Dita D   Peters Björn B   Kerschbaum Julia J   Leierer Johannes J   Neprasova Michaela M   Banasik Miroslaw M   Sanz Ana Belen AB   Perez-Gomez Maria Vanessa MV   Ortiz Alberto A   Stegmayr Bernd B   Tesar Vladimir V   Mischak Harald H   Beige Joachim J   Reich Heather N HN  

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20211201 1


<h4>Background</h4>Risk of kidney function decline in immunoglobulin A (IgA) nephropathy (IgAN) is significant and may not be predicted by available clinical and histological tools. To serve this unmet need, we aimed at developing a urinary biomarker-based algorithm that predicts rapid disease progression in IgAN, thus enabling a personalized risk stratification.<h4>Methods</h4>In this multicentre study, urine samples were collected in 209 patients with biopsy-proven IgAN. Progression was define  ...[more]

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