Proteomics

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CDS composition drives differential regulation of mRNA fate by the Ccr4-Not complex


ABSTRACT: Regulation of protein output at the level of translation allows for a swift response to dynamic changes in the requirements of the cell. This is achieved by a complex set of biochemical processes that regulate protein synthesis and mRNA stability. A major factor coordinating this regulation is the Ccr4-Not complex. Despite playing a role in most stages of the mRNA life cycle, no attempt has been made to take a global integrated view of how the Ccr4-Not complex affects gene expression. Bioreplicate one for this paper is available at the Proteome xchange identifier: PXD014764

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Kelly Hodge  

LAB HEAD: Sara Zanivan

PROVIDER: PXD020305 | Pride | 2021-10-11

REPOSITORIES: Pride

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