Proteomics

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Proteome characteristics of Tolypocladium guangdongense at differentically developmental stages

ABSTRACT: Tolypocladium guangdongense has a similar metabolite profile to Ophiocordyceps sinensis, a highly regarded fungus used for traditional Chinese medicine with high nutritional and medicinal value. Although the genome sequence of T. guangdongense has been reported, relatively little is known about the regulatory networks for fruiting body development and about the metabolite biosynthesis pathways. In order to address this, an analysis of proteome at differentially developmental stages of T. guangdongense was performed. Many heat shock proteins, transcription factors and proteins related to active ingredients were differentially expressed during the developmental process. These data could be meaningful and useful for studying the molecular mechanisms of fungal development, and for the industrial and medicinal application of macro-fungi.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Cordyceps Guangdongensis

TISSUE(S): Fruit Body, Primordium, Mycelium

SUBMITTER: Gang Wang  

LAB HEAD: Tai Hui Li

PROVIDER: PXD020391 | Pride | 2021-09-09

REPOSITORIES: Pride

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Action DRS
19P0476_all.mgf Mgf
F19FTSSCKF1426_J191216036_canonical.fasta Fasta
F19FTSSCKF1426_J191216036_rep1-peptideSummary.xls Xls
F19FTSSCKF1426_J191216036_rep1.dat Other
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Publications

Transcriptome and proteome analyses reveal the regulatory networks and metabolite biosynthesis pathways during the development of <i>Tolypocladium guangdongense</i>.

Wang Gangzheng G   Li Min M   Zhang Chenghua C   Cheng Huijiao H   Gao Yu Y   Deng Wangqiu W   Li Taihui T  

Computational and structural biotechnology journal 20200725

<i>Tolypocladium guangdongense</i> has a similar metabolite profile to <i>Ophiocordyceps sinensis</i>, a highly regarded fungus used for traditional Chinese medicine with high nutritional and medicinal value. Although the genome sequence of <i>T. guangdongense</i> has been reported, relatively little is known about the regulatory networks for fruiting body development and about the metabolite biosynthesis pathways. In order to address this, an analysis of transcriptome and proteome at differenti  ...[more]

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