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Deciphering the kinesin-8B role during Plasmodium berghei gametogenesis by a proteomic approach

ABSTRACT: We focused on the iTRAQ-based quantitative proteomic characterization of rodent parasite Plasmodium berghei mutants with disrupted kinesin-8B gene compared to wild type within the gamete differentiation. Time-course analyses were performed 7 and 15 min after gametogenesis induction (Time 0).

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Plasmodium Berghei Anka Mus Musculus (mouse)

TISSUE(S): Blood Cell, Blood

DISEASE(S): Plasmodium Falciparum Malaria

SUBMITTER: SEBASTIEN CHARNEAU

LAB HEAD: Sébastien Charneau

PROVIDER: PXD020911 | Pride | 2021-04-17

REPOSITORIES: Pride

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			Action	DRS
	Duplex_T7_Wt_vs_K8_Biological_replicate1_Techical_replicate1.raw	Raw
	Duplex_T7_Wt_vs_K8_Biological_replicate1_Techical_replicate1.sqt	Other
	Duplex_T7_Wt_vs_K8_Biological_replicate1_Techical_replicate2.raw	Raw
	Duplex_T7_Wt_vs_K8_Biological_replicate1_Techical_replicate2.sqt	Other
	Duplex_T7_Wt_vs_K8_Biological_replicate2_Techical_replicate1.raw	Raw

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Dynamic molecular events associated to Plasmodium berghei gametogenesis through proteomic approach

Project description:We carried out a iTRAQ-based quantitative proteomic insight into the rodent parasite Plasmodium berghei gamete morphogenesis providing valuable time course data. Time-course analyses were performed 7 and 15 min after gametogenesis induction (Time 0).

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