Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Drosophila Melanogaster (fruit Fly)
TISSUE(S): Whole Body
DISEASE(S): Disease Free
SUBMITTER: Gao yue
LAB HEAD: Mingyao Yang
PROVIDER: PXD021022 | Pride | 2021-09-09
REPOSITORIES: Pride
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Gao Yue Y Zhu Chenxing C Li Keqin K Cheng Xingyi X Du Yanjiao Y Yang Deying D Fan Xiaolan X Gaur Uma U Yang Mingyao M
PloS one 20201016 10
To explore the underlying mechanism of dietary restriction (DR) induced lifespan extension in fruit flies at protein level, we performed proteome sequencing in Drosophila at day 7 (young) and day 42 (old) under DR and ad libitum (AL) conditions. A total of 18629 unique peptides were identified in Uniprot, corresponding to 3,662 proteins. Among them, 383 and 409 differentially expressed proteins (DEPs) were identified from comparison between DR vs AL at day 7 and 42, respectively. Bioinformatics ...[more]